Cholera Toxin beta Antikörper (HRP)

Produktnummer ABIN1710863

Der Kaninchen Polyklonal Anti-Cholera Toxin beta-Antikörper wurde für WB, ELISA, IHC (fro) und IHC (p) validiert. Er ist geeignet, Cholera Toxin beta in Proben von Vibrio cholerae zu detektieren.

Kurzübersicht für Cholera Toxin beta Antikörper (HRP) (ABIN1710863)

Target: Cholera Toxin beta

Reaktivität: Vibrio cholerae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cholera Toxin beta Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Cholera Toxin beta Antikörper (HRP)

Kreuzreaktivität: Ratte

Kreuzreaktivität (Details): Cholera Toxin Subunit B

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from CTXB/beta subunit Cholera Toxin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Gentamicin sulfate

Vorsichtsmaßnahmen: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Cholera Toxin beta

Target: Cholera Toxin beta

Hintergrund:

Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin beta chain, Cholera enterotoxin gamma chain, Cholera enterotoxin subunit B, Cholera toxin B protein, Choleragenoid, CTX B, CTXB, TOX B, TOXB, VC1456, CHTB_VIBCH.

Background: The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

Gen-ID: 2613962